Add this assembly at the top of the aspx page

<%@ Register Assembly="AjaxControlToolkit" Namespace="AjaxControlToolkit" TagPrefix="asp" %>

then in the content section

Use a scriptmanager. note: do not use multiple scriptmanager. if u already have scriptmanager in the master page then dont need to add to the aspx page.

<asp:UpdatePanel ID="UpdatePanel1" runat="server">
<ContentTemplate>

</ContentTemplate> </asp:UpdatePanel>

have fun